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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 2
1987 1
1989 2
1994 2
1998 1
2005 1
2006 1
2007 2
2008 2
2009 3
2010 2
2011 4
2012 4
2013 6
2014 11
2015 9
2016 10
2017 6
2018 11
2019 14
2020 11
2021 12
2022 9
2023 10
2024 5

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119 results

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Page 1
ZBP1 Protects Against mtDNA-Induced Myocardial Inflammation in Failing Hearts.
Enzan N, Matsushima S, Ikeda S, Okabe K, Ishikita A, Yamamoto T, Sada M, Miyake R, Tsutsui Y, Nishimura R, Toyohara T, Ikeda Y, Shojima Y, Miyamoto HD, Tadokoro T, Ikeda M, Abe K, Ide T, Kinugawa S, Tsutsui H. Enzan N, et al. Circ Res. 2023 Apr 28;132(9):1110-1126. doi: 10.1161/CIRCRESAHA.122.322227. Epub 2023 Mar 28. Circ Res. 2023. PMID: 36974722 Free PMC article.
BACKGROUND: Mitochondrial DNA (mtDNA)-induced myocardial inflammation is intimately involved in cardiac remodeling. ZBP1 (Z-DNA binding protein 1) is a pattern recognition receptor positively regulating inflammation in response to mtDNA in inflammatory cells, fibrob …
BACKGROUND: Mitochondrial DNA (mtDNA)-induced myocardial inflammation is intimately involved in cardiac remodeling. ZBP1 (Z-DNA bindi …
Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relevance for real-time quantitative PCR.
Bednarz-Misa I, Neubauer K, Zacharska E, Kapturkiewicz B, Krzystek-Korpacka M. Bednarz-Misa I, et al. Adv Clin Exp Med. 2020 May;29(5):547-556. doi: 10.17219/acem/118845. Adv Clin Exp Med. 2020. PMID: 32424999 Free article.
BACKGROUND: The effect of bowel inflammation and cancer on the expression of the most prevalent internal controls: ACTB, GAPDH and B2M in whole blood is unknown, although at least GAPDH occurred to be tightly regulated and suspected of supporting cancer growth, chal …
BACKGROUND: The effect of bowel inflammation and cancer on the expression of the most prevalent internal controls: ACTB, GAPDH and …
Identification of immune cell infiltration and diagnostic biomarkers in unstable atherosclerotic plaques by integrated bioinformatics analysis and machine learning.
Wang J, Kang Z, Liu Y, Li Z, Liu Y, Liu J. Wang J, et al. Front Immunol. 2022 Sep 23;13:956078. doi: 10.3389/fimmu.2022.956078. eCollection 2022. Front Immunol. 2022. PMID: 36211422 Free PMC article.
The proportions of M0, M1, and M2 macrophages were significantly higher and that of CD8(+) T cells and NK cells were significantly lower in unstable plaques than that in stable plaques. With respect to DEGs, antigen presentation genes (CD74, B2M, and HLA-DRA), inflammat
The proportions of M0, M1, and M2 macrophages were significantly higher and that of CD8(+) T cells and NK cells were significantly lower in …
Combination of single-cell and bulk RNA seq reveals the immune infiltration landscape and targeted therapeutic drugs in spinal cord injury.
Zhang Q, Yu B, Zhang Y, Tian Y, Yang S, Chen Y, Wu H. Zhang Q, et al. Front Immunol. 2023 Jan 19;14:1068359. doi: 10.3389/fimmu.2023.1068359. eCollection 2023. Front Immunol. 2023. PMID: 36742334 Free PMC article.
Among the immune microenvironment components, macrophages/microglia play a dual role of pro-inflammation and anti-inflammation in the subacute stage of SCI. Therefore, discovering the immune hub genes and targeted therapeutic drugs of macrophages/microglia after SCI …
Among the immune microenvironment components, macrophages/microglia play a dual role of pro-inflammation and anti-inflammation
Cell-free protein synthesis of CD1E and B2M protein and in vitro interaction.
Tang Y, Ma S, Lin S, Wu Y, Chen S, Liu G, Ma L, Wang Z, Jiang L, Wang Y. Tang Y, et al. Protein Expr Purif. 2023 Mar;203:106209. doi: 10.1016/j.pep.2022.106209. Epub 2022 Nov 29. Protein Expr Purif. 2023. PMID: 36460227
Furthermore, we used the string website to predict the protein interaction network of CD1E and identified a potential binding partnerB2M. Similarly, we synthesized soluble B2M in the E.coli CFPS. Finally, we verified the interaction between CD1E and B2M by using Sur …
Furthermore, we used the string website to predict the protein interaction network of CD1E and identified a potential binding partnerB2M. Si …
Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina.
Church KA, Rodriguez D, Vanegas D, Gutierrez IL, Cardona SM, Madrigal JLM, Kaur T, Cardona AE. Church KA, et al. J Neuroinflammation. 2022 Dec 14;19(1):300. doi: 10.1186/s12974-022-02659-9. J Neuroinflammation. 2022. PMID: 36517889 Free PMC article.
Confocal microscopy revealed that PLX-5622 also induced an increase in TUJ1(+) axonal density and prevented fibrinogen extravasation into the diabetic retina. mRNAseq gene expression analysis in retinal isolates revealed that PLX-5622-induced microglia depletion and repopulation …
Confocal microscopy revealed that PLX-5622 also induced an increase in TUJ1(+) axonal density and prevented fibrinogen extravasation into th …
An outlook on biomarkers in cardiogenic shock.
Iborra-Egea O, Montero S, Bayes-Genis A. Iborra-Egea O, et al. Curr Opin Crit Care. 2020 Aug;26(4):392-397. doi: 10.1097/MCC.0000000000000739. Curr Opin Crit Care. 2020. PMID: 32452847 Review.
The CS4P score is based on the levels of liver fatty acid-binding protein (L-FABP), beta-2-microglobulin (B2M), fructose-bisphosphate aldolase B (ALDOB), and SerpinG1 (IC1). These proteins are not cardiac-specific but reflect multiorgan dysfunction, systemic inflammatio
The CS4P score is based on the levels of liver fatty acid-binding protein (L-FABP), beta-2-microglobulin (B2M), fructose-bisphosphate …
Mitochondrial DNA Changes in Blood and Urine Display a Specific Signature in Relation to Inflammation in Normoalbuminuric Diabetic Kidney Disease in Type 2 Diabetes Mellitus Patients.
Petrica L, Vlad A, Gadalean F, Muntean DM, Vlad D, Dumitrascu V, Bob F, Milas O, Suteanu-Simulescu A, Glavan M, Jianu DC, Ursoniu S, Balint L, Mogos-Stefan M, Ienciu S, Cretu OM, Popescu R. Petrica L, et al. Int J Mol Sci. 2023 Jun 6;24(12):9803. doi: 10.3390/ijms24129803. Int J Mol Sci. 2023. PMID: 37372951 Free PMC article.
MtDNA-CN was defined as the ratio of the number of mtDNA/nDNA copies via analysis of the CYTB/B2M and ND2/B2M ratio. Multivariable regression analysis provided models in which serum mtDNA directly correlated with IL-10 and indirectly correlated with UACR, IL-17A, an …
MtDNA-CN was defined as the ratio of the number of mtDNA/nDNA copies via analysis of the CYTB/B2M and ND2/B2M ratio. Multivari …
Relationships between renal parameters and serum and urine markers of inflammation in those with and without HIV infection.
Shinha T, Mi D, Liu Z, Orschell CM, Lederman MM, Gupta SK. Shinha T, et al. AIDS Res Hum Retroviruses. 2015 Apr;31(4):375-83. doi: 10.1089/AID.2014.0234. Epub 2015 Feb 26. AIDS Res Hum Retroviruses. 2015. PMID: 25646974 Free PMC article.
When combining all four study groups, statistically significant positive correlations included uPCR with urine IL-8, urine MCP-1, urine IP-10, and serum IP-10 and uACR with urine IL-8, urine B2M, serum IP-10, and serum B2M. eGFR was statistically significantly negat …
When combining all four study groups, statistically significant positive correlations included uPCR with urine IL-8, urine MCP-1, urine IP-1 …
Comparative Analysis of Molecular Landscape in Mouse Models and Patients Reveals Conserved Inflammation Pathways in Age-Related Macular Degeneration.
Liu YS, Pan JQ, Pan XB, Kong FS, Zhang JQ, Wei ZY, Xu ZH, Rao JH, Wang JH, Chen JH. Liu YS, et al. Invest Ophthalmol Vis Sci. 2024 Jan 2;65(1):13. doi: 10.1167/iovs.65.1.13. Invest Ophthalmol Vis Sci. 2024. PMID: 38175639 Free PMC article.
Proteomic analysis further validated these differentially expressed genes and their networks in retinal inflammation during CNV. Notably, the most evident overlap in the retina of mice with laser-induced CNV and NaIO3-induced RD was the upregulation of inflammation- …
Proteomic analysis further validated these differentially expressed genes and their networks in retinal inflammation during CNV. Nota …
119 results